A wide variety of cutaneous manifestations of lupus erythematosus have
been reported. Among them, papulonodular eruptions produced by dermal
mucin deposition have been recognized as nodular cutaneous lupus muci
nosis (NCLM), and many cases have been reported in Japan, A 21-year-ol
d woman with systemic lupus erythematosus (SLE) showed papulonodular e
ruptions on her back. A skin specimen from the nodule revealed mucin d
eposition (hyaluronic acid) in the dermis. NCLM should be recognized a
s a clinical form associated with SLE. The pathogenesis of the mucin d
eposition in NCLM is still uncertain.