G. Putz et al., SURFACTANT REPLACEMENT THERAPY IN ACUTE RESPIRATORY-DISTRESS SYNDROMEFROM VIRAL PNEUMONIA, Intensive care medicine, 22(6), 1996, pp. 588-590
A modified natural surfactant was administered to a patient with life-
threatening adult respiratory distress syndrome caused by viral pneumo
nia. Subsequently, there was a marked improvement in gas exchange. In
order to assess the mechanism for improved oxygenation, computed tomog
raphy of the lungs was done. Quantitative analysis of the scans taken
before and after surfactant administration indicates that improvement
in gas exchange was largely due to the expansion of underinflated and
collapsed lung areas. Although this is a single case report, it provid
es insight into the possible beneficial effect of instilled surfactant
in severe respiratory distress from viral pneumonia.