OPTIMAL-DESIGN OF N-CSTRS IN SERIES USING MICHAELIS-MENTEN ONE-SUBSTRATE REVERSIBLE-REACTION

Exact analytical expressions are derived for the optimal design (minim um overall reaction volume) of N CSTRs in series carrying out an enzym e catalysed Michaelis-Menten one-substrate one-product reversible reac tion. These equations enable the direct calculation of the smallest to tal reactor volume (holding time) needed for a given overall conversio n degree, as well as the individual reactor Volume and conversion degr ees. Results are also compared with the ones obtained for a single tan k and for a plug now reactor.