MONOHEXOSYLCERAMIDES OF TRYPANOSOMA-DIONISII

A detailed knowledge of the primary structure of neutral glycosphingol ipids isolated and purified from Trypanosoma dionisii has been elucida ted using a combination of techniques-as column chromatography. HPTLC and GC-MS together with fast atom bombardment spectrometry. The cerami de monohexoside fraction (CMH) contained both glucosyl- and galactosyl ceramides in a ratio of 1:1. sphingosine and as fatty acyl groups main ly C-24 saturated and 2-hydroxy fatty acids. A close similarity betwee n Trypanosoma cruzi and T. dionisii monohexosylceramides was reported.