A SHORT SYNTHESIS OF (Z)-15-METHYLHEXADEC-11-ENOIC ACID

Authors
REYES ED CARBALLEIRA NM
Citation
Ed. Reyes et Nm. Carballeira, A SHORT SYNTHESIS OF (Z)-15-METHYLHEXADEC-11-ENOIC ACID, Synthesis, (6), 1996, pp. 693
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
6
Year of publication
1996
Database
ISI
SICI code
0039-7881(1996):6<693:ASSO(A>2.0.ZU;2-V
Abstract
The biologically intriguing (Z)-15-methylhexadec-11-enoic acid, a comp onent of Myxococcus xanthus and Cyamopsis tetragonolobus, has been syn thesized in 19% overall yield via the Wittig reaction of 4-methyl-1-pe ntyltriphenylphosphonium bromide and 10-bromodecanal. The title compou nd displayed marginal cytotoxicity against human cervix carcinoma (HeL a) and Chinese hamster ovary (CHO) cells.