L. Eggers et W. Grahn, 4-ALKYL-SUBSTITUTED AND 4-BENZYL-SUBSTITUTED 3,3'-OXYBISPYRIDINES - AN EFFICIENT SYNTHESIS AT ROOM-TEMPERATURE, Synthesis, (6), 1996, pp. 763
Several new 4-alkyl- and 4-benzyl-substituted 3,3'-oxybispyridines 1 a
re accessible at room temperature in high yields from 3-hydroxypyridin
e, potassium salt derivatives 7 and 3-bromo-4-nitropyridine 1-oxide (5
d), which are readily available starting materials. The reactivity of
5d depends on the solvent.