BOTULINUM TOXIN INJECTION INTO VOCAL CORD IN THE TREATMENT OF MALIGNANT COPROLALIA ASSOCIATED WITH TOURETTES-SYNDROME

We describe a 13-year-old boy with Tourette's syndrome (TS) manifested chiefly by severe coprolalia, obsessive compulsive disorder, and atte ntion deficit hyperactivity disorder. He was treated with unilateral i njections of botulinum toxin to the vocal cord and experienced marked improvement in coprolalia as well as marked reduction in the premonito ry urges associated with the vocal ties and coprolalia. As a result of the improvement, the patient was able to attend school and church and was able to socialize. Botulinum toxin may interfere with a sensory r eflex arc required to perpetuate ties and coprolalia in TS, possibly b y reducing local build-up of tension or muscle contraction in affected areas.