ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN PATIENTS WITH IDIOPATHIC ULCERATIVE-COLITIS

Citation
G. Rojas et al., ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN PATIENTS WITH IDIOPATHIC ULCERATIVE-COLITIS, Revista Medica de Chile, 124(4), 1996, pp. 449-455
Citations number
34
Categorie Soggetti
Medicine, General & Internal
Journal title
ISSN journal
00349887
Volume
124
Issue
4
Year of publication
1996
Pages
449 - 455
Database
ISI
SICI code
0034-9887(1996)124:4<449:ACAIPW>2.0.ZU;2-9
Abstract
We studied the presence of antineutrophil cytoplasmic antibodies in 16 patients with idiopathic ulcerative colitis, using an indirect immuno fluorescence technique and specific ELISA for myeloperoxidase and prot einase 3. Twelve patients had an active disease and in ten, antineutro phil cytoplasmic antibodies were positive, with a predominantly perinu clear distribution and without specificity for myeliperoxidase or prot einase 3. These antibodies were negative in the four patients with ina ctive disease. It is concluded that antineutrophil cytoplasmic antibod ies could be serologic indicators of disease activity in patients with ulcerative colitis.