ANALYSIS OF URINARY CALCULI CONTAINING TRIAMTERENE - PRESENCE OF A GLUCURONIC METABOLITE

Authors
SABOT JF BERNARD P PINATEL H BOUCHERAT M
Citation
Jf. Sabot et al., ANALYSIS OF URINARY CALCULI CONTAINING TRIAMTERENE - PRESENCE OF A GLUCURONIC METABOLITE, Analytical letters, 29(8), 1996, pp. 1319-1327
Citations number
15
Categorie Soggetti
Chemistry Analytical
Journal title
Analytical letters → ACNP
ISSN journal
00032719
Volume
29
Issue
8
Year of publication
1996
Pages
1319 - 1327
Database
ISI
SICI code
0003-2719(1996)29:8<1319:AOUCCT>2.0.ZU;2-G
Abstract
Urinary calculi containing triamterene were described since 1979. We h ave studied calculi, obtained from an anuric patient, by surgery. This paper describes the advanced techniques that were used, such as infra red spectroscopy, nuclear magnetic resonance, mass spectrometry associ ated with thin-layer chromatography or gas chromatography, to show the presence of unusual compounds. Six metabolites are found, among them pure triamterene (96%), hydroxy-triamterene, and a particular metaboli te containing glucuronic acid.