D. Cochelard et al., DEVELOPMENT OF A NEW SOFTWARE FOR AN INTERACTIVE ANALYSIS OF PARTICLE-SIZE, Drug development and industrial pharmacy, 22(7), 1996, pp. 721-730
The aim of this work is to propose a new software for a more precise e
valuation, computation, and visualization of characteristic parameters
of particle size distribution. The software is created upon the build
ing block concept, the outputs of each block being automatically conne
cted to the other blocks, allowing a great level of interactivity. The
principal characteristics printed or plotted are: (a) analysis menu (
calculated outputs): summary tables of the aperture size of the sieves
and their individual and cumulative associated percentage and correct
ed percentage, when a loss of powder occurs during the weighing of the
different sieves; (b) graphic menu (calculated and plotted outputs):
(i) bar chart of the individual percentages against the size of the si
eves, (ii) Polygon of the cumulative percentages against the size of t
he sieves, (iii) Histograms and cumulative percentage polygon together
, (iv) observed points evaluating the probit of the cumulative weight
percentage against the logarithm of the aperture size of the sieves, (
v) regression lines and their equation coefficients, (vi) the results
of the chi-square test, associated to the calculation of the chosen re
gression equation, with its probability level and the interpretation o
f the test (linearity reject or linearity no reject), (vii) the mean d
iameter or diameter corresponding to any fractile and their confidence
intervals, (viii) comparison between several regression lines, and (i
x) friability test.