DEVELOPMENT OF A NEW SOFTWARE FOR AN INTERACTIVE ANALYSIS OF PARTICLE-SIZE

Citation
D. Cochelard et al., DEVELOPMENT OF A NEW SOFTWARE FOR AN INTERACTIVE ANALYSIS OF PARTICLE-SIZE, Drug development and industrial pharmacy, 22(7), 1996, pp. 721-730
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy
ISSN journal
03639045
Volume
22
Issue
7
Year of publication
1996
Pages
721 - 730
Database
ISI
SICI code
0363-9045(1996)22:7<721:DOANSF>2.0.ZU;2-9
Abstract
The aim of this work is to propose a new software for a more precise e valuation, computation, and visualization of characteristic parameters of particle size distribution. The software is created upon the build ing block concept, the outputs of each block being automatically conne cted to the other blocks, allowing a great level of interactivity. The principal characteristics printed or plotted are: (a) analysis menu ( calculated outputs): summary tables of the aperture size of the sieves and their individual and cumulative associated percentage and correct ed percentage, when a loss of powder occurs during the weighing of the different sieves; (b) graphic menu (calculated and plotted outputs): (i) bar chart of the individual percentages against the size of the si eves, (ii) Polygon of the cumulative percentages against the size of t he sieves, (iii) Histograms and cumulative percentage polygon together , (iv) observed points evaluating the probit of the cumulative weight percentage against the logarithm of the aperture size of the sieves, ( v) regression lines and their equation coefficients, (vi) the results of the chi-square test, associated to the calculation of the chosen re gression equation, with its probability level and the interpretation o f the test (linearity reject or linearity no reject), (vii) the mean d iameter or diameter corresponding to any fractile and their confidence intervals, (viii) comparison between several regression lines, and (i x) friability test.