NCI-NAVY MEDICAL ONCOLOGY BRANCH CELL-LINE DATA-BASE

The cell line data base described in this paper includes both clinical information about the patients from whom the cell lines were derived and information about the in vitro analyses performed of the cell line s. The cell line data base has evolved as a part of a systematic effor t by a research group at the NCl since 1976 to generate human cell lin es as biological toots to study cancer and other diseases. The cell li nes were generated from clinical specimens obtained as part of a serie s of Institutional Review Board-approved clinical protocols, The prepo nderance of the data is on lung cancer cell lines, though a broad rang e of other cancers are represented. A bank of over 300 human cell line s including cancer cell and in some instances autologous B-lymphoblast oid cells from the NCI-VA and NCI-Navy Medical Oncology Branch are rep osited at the American Type Culture Collection. The cell lines are ava ilable for the research community. The entire database is available on the American Type Culture Collection Web Site (WWW:http://www.atcc.or g/). (C) 1996 Wiley-Liss, Inc.