TIME REVERSIBILITY OF INTRACRANIAL HUMAN EEG RECORDINGS IN MESIAL TEMPORAL-LOBE EPILEPSY

Intracranial electroencephalograms from patients suffering from mesial temporal lobe epilepsy were tested for time reversibility. If the rec orded time series is irreversible, the input of the recording system c annot be a realisation of a linear Gaussian random process, We confirm ed experimentally that the measurement equipment did not introduce irr eversibility in the recorded output when the input was a realisation o f a linear Gaussian random process, In general, the non-seizure record ings are reversible, whereas the seizure recordings are irreversible. These results suggest that time reversibility is a useful property for the characterisation of human intracranial EEG recordings in mesial t emporal lobe epilepsy.