We study supersymmetric unified models with three fermion generations
based on the gauge group SO(10) and require gauge-Yukawa unification,
i.e. a renormalization group invariant functional relationship among t
he gauge and Yukawa couplings of the third generation in the symmetric
phase. In the case of the minimal model, we find that the predicted v
alues for the top and bottom quark masses are in agreement with the pr
esent experimental data for a wide range of supersymmetry breaking sca
les, We also find that an experimental accuracy of less than 1% for th
e top quark mass could test the corresponding prediction of the gauge-
Yukawa unified model.