V. Thomas et al., ASSESSMENT OF PROCEDURAL MEMORY IN PARKINSONS-DISEASE, Progress in neuro-psychopharmacology & biological psychiatry, 20(4), 1996, pp. 641-650
1. Findings in cognitive psychology and neuropsychology have led to co
nsider the existence of several mnestic systems. This study focusses o
n a now clearly established distinction between the procedural and the
declarative memories. 2. The aim of the present study was to try and
determine which of the two acquisition steps (learning and automation)
is affected by Parkinsonians' mnestic difficulties, and to verify if
these difficulties are linked to the skill content (declarative or mot
or). 3. To answer these questions, 20 Parkinsonians under treatment un
derwent specific tests : the maze test and the arithmetic alphabet tes
t. 4. Results show that, by comparison with 20 matched healthy individ
uals, the deficiencies observed in Parkinson's disease affect both the
declarative and the motor skills. In addition, Parkinsonians suffer d
ifficulties in both acquisition steps: learning and automation. 5. The
se results could account for the cognitive and motor disturbances obse
rved in Parkinson's disease; these abnormalities should be among the p
harmacological targets in future.