While fairly complete and reliable incident data on childhood cancers
are available from the registries in India, mortality and survival inf
ormation is not. Information concerning the latter was obtained by the
Bangalore cancer registry through active follow-up involving visits t
o homes of patients. Between 1982 and 1989, 617 cases of cancers in ch
ildhood were registered, giving an age-standardized incidence rate of
84.8 and 48.4 per million in male and female children, respectively. A
ctive follow-up provided mortality/survival information in 532 or 86.2
percent of these cases. Overall, observed five-year survival was 36.8
percent (both genders combined) with a relative survival of 37.5 perc
ent when childhood mortality in the general population was taken into
account. The five-year relative survival was best for thyroid carcinom
a (100 percent) followed by Hodgkin's disease (73 percent) and retinob
lastoma (72.9 percent). Survival was comparatively low,being 9.9 perce
nt in acute nonlymphatic leukemia and less than 20 percent in rhabdomy
osarcoma and the category grouped as 'other malignant neoplasms.' Surv
ival in Hodgkin's disease was influenced by clinical stage at presenta
tion, but was not statistically significant possibly due to small numb
ers.