O. Speck et al., GRADING AND THERAPY MONITORING OF ASTROCYTOMAS WITH H-1-SPECTROSCOPY - PRELIMINARY-STUDY, Anticancer research, 16(3B), 1996, pp. 1581-1585
We examined 11 patients (9 male and 2 female, age 41 +/- 13) presentin
g astrocytomas of different malignancy grade (WHO) with single voxel (
PRESS) and double voxel (STABLE) spectroscopy techniques. The content
of choline in the tumors was determined as a function of their grade o
f malignity and a significant correlation was found. The measurements
were repeated after interstitial radiosurgery. Observed spectra change
s induced by this stereotactic treatment with I-125-seed demonstrated
the possibility of therapy monitoring.