Original methods for controlling the oestrous cycle of cattle were bas
ed on extending or reducing the luteal phase to produce a synchronised
decline in concentrations of progesterone or a synthetic progestagen.
Modifications with GnRH or oestradiol at treatment initiation can alt
er patterns of ovarian follicle development to synchronise the emergen
ce of a new dominant follicle. Otherwise, dominance can persist and th
e synchronised oestrus may be associated with reduced fertility. Avoid
ing this effect may increase variation in the duration of pro-oestrus
and complicate inseminating animals at a prescribed post-treatment int
erval (timed insemination). Using oestradiol, GnRH or hCG during pro-o
estrus can reduce variation in the interval to ovulation, Timing of th
ese pro-oestrous treatments is important if the effects of inducing pr
emature ovulations are to be avoided. Oestradiol has also been shown t
o be more effective than eCG as a pro-oestrous treatment with anoestro
us dairy cows, allowing them to be included in synchrony programmes in
itially using progesterone supplementation. Current trials are investi
gating techniques for processing semen for use with inseminations made
during pro-oestrus. Finally, concepts of oestrous cycle control to im
prove reproductive efficiency should be extended to include re-synchro
nisation of returns to service and the further development of treatmen
ts which increase the probability of conceptus recognition. Effective
oestrous cycle control to improve reproductive efficiency may require
modifications to ovarian follicle patterns when the treatment is initi
ated, as well as during pro-oestrus and at a specified period in the c
ycle following insemination.