The physician who is entrusted with a large quantity of resources for
the treatment of ARF/MOSF has a social responsibility for optimizing t
he treatment, auditing the outcome, and where possible, preventing the
illness. Best treatment includes not only modem techniques bur also e
fficient organization and leadership of the ICU team. Audit is an indi
vidual responsibility, may be fruitfully pursued on a multicenter basi
s, and is a cost-containment discipline. Audit of the St. Thomas' Hosp
ital ARF program has resulted in a predictive scoring formula. This is
used to illustrate a cost-effective analysis related to disease sever
ity Prevention of ARF/MOSF is a challenge to emergency services. There
may also be a considerable opportunity to prevent ARF in highrisk sur
gical patients. A randomized study carried our at St. George's Hospita
l illustrates the health gains which could result.