ESOPHAGEAL AND DUODENAL ATRESIA IN A FETUS WITH DOWNS-SYNDROME - PRENATAL SONOGRAPHIC FEATURES

Ultrasound examination of a 22-week fetus demonstrated a grossly diste nded stomach and proximal duodenum, with a large cystic area in the ch est. There was associated polyhydramnios. A presumptive diagnosis of d uodenal atresia with a congenital diaphragmatic hernia was made. Analy sis of a fetal blood sample showed that the fetus had Down's syndrome. Histological examination after termination of the pregnancy revealed the unusual combination of duodenal and esophageal atresia, with an in tact diaphragm.