REVERSIBLE PAROTID ENLARGEMENT AND PSEUDO-SJOGRENS SYNDROME SECONDARYTO HYPERTRIGLYCERIDEMIA

We describe 2 patients with a Sjogren-like syndrome apparently seconda ry to hypertriglyceridemia. Both had bilateral parotitis in addition t o musculoskeletal and sicca symptoms. Parotid gland histology revealed fatty infiltration with no inflammation. Therapy with dietary modific ation and triglyceride lowering drugs resulted in resolution of sympto ms and parotid swelling in one patient. Zn the 2nd patient, hypertrigl yceridemia was resistant to triglyceride lowering drugs, and parotid s ymptoms and swelling continued unabated. Our findings suggest aggressi ve treatment of hyperlipidemia in pseudo-Sjogren's syndrome may result in amelioration of musculoskeletal and parotid symptoms.