THE ASSOCIATION OF SYSTEMIC LUPUS-ERYTHEMATOSUS AND LAMBERT-EATON MYASTHENIC SYNDROME

The association of systemic lupus erythematosus (SLE) and myasthenia g ravis is well known, However, the association between SLE and Lambert- Eaton myasthenic syndrome (LEMS) is described in only 2 cases. We desc ribe the case of a 31-year-old woman with SLE who presented with sever e, predominantly proximal muscle weakness of subacute onset. The diagn osis of LEMS was based on her distinctive clinical and electrophysiolo gical findings. She was treated successfully with plasmapheresis and o ral prednisone. She remains in remission 6 months after this episode.