PITUITARY INSUFFICIENCY AND REGRESSION OF ACROMEGALY CAUSED BY PITUITARY APOPLEXY FOLLOWING CEREBRAL-ANGIOGRAPHY

Pituitary apoplexy as a complication of cerebral angiography has been described in only a few case reports. Some studies have reported the c linical resolution of active acromegaly after pituitary apoplexy. We p resent a patient with active acromegaly due to a growth hormone (GH)-s ecreting pituitary macroadenoma, who developed anterior and posterior pituitary insufficiency following cerebral angiography. Furthermore, a significant reduction in tumour size was accompanied by normalization of mean 24 h in GH insulin-like growth factor I (IGF-I) and IGF bindi ng protein 3 levels.