Psychosexual functioning of opioid-dependent women (N = 63) was compar
ed to a socioeconomically similar group of non-drug-abusing women (N =
53) using the Derogatis Sexual Functioning Inventory (DSFI). Initial
analyses revealed differences in sexual drive, liberal attitude, and b
oth masculine and feminine gender-role affiliation. When demographic d
ifferences between the two groups were statistically controlled howeve
r, only liberal attitude and femininity subscale differences remained
significant. Although both opioid-dependent and comparison group women
reported similar types of sexual experiences (lifetime), opioid-depen
dent women reported greater recent reduction in sexual behaviors relat
ed to anal intercourse and anal stimulation. Both opioid-dependent and
clinic women differed significantly from the DSFI normative sample, h
ighlighting the importance of controlling for demographic differences
when using standardized psychological assessment tools. Implications o
f study findings for AIDS prevention and intervention with drug-depend
ent women are discussed.