Semistructured interviews were carried out with 20 illicit users of ke
tamine in Scotland. Participants had used a wide range of illegal drug
s. Scottish drug agencies reported limited contact with ketamine users
; however, subjects were knowledgeable regarding the licit purpose of
ketamine, its effects, and its legal status. Ketamine was usually obta
ined through diversion from legitimate sources. Three participants rep
orted extensive use, indicating the potential for psychological depend
ence. A standard dose of ketamine was typically 1/8 g, usually taken i
ntranasally. Participants reported the ketamine experience as king ext
remely intense and dissociative, usually lasting for approximately one
hour. An participants reported using ketamine in a carefully preplann
ed setting, emphasizing comfort, security, and familiarity. Participan
ts identified potential problems arising from using ketamine in a publ
ic place, or in unfamiliar surroundings, and also suggested that novic
e users may encounter problems through lack of knowledge concerning th
e intense nature of the experience. Accurate information concerning th
e effects and nature of ketamine as well as the importance of set and
setting should be made available. However, publicizing the drug should
be avoided as widespread interest could cause greater problems than-c
urrently exist.