INVESTIGATION OF TRACE-ELEMENTS IN CANCER KIDNEY TISSUES BY SRIXE ANDPIXE

In November 1994 we performed some preliminary studies on cancer kidne y tissues. The objective of the measurements was to find a difference in trace element concentrations between normal and cancerous kidney ti ssue. All targets were prepared as pellets of more or less the same we ight and thickness. Kidney samples were obtained during surgical opera tions done in the Clinic of Urology in Cracow. All kidneys were subjec t to removal due to cancer disease. Samples for analysis were taken fr om the cancerous part of the kidney and the non-cancerous one. Ail sam ples were analyzed by means of SRIXE (Synchrotron Radiation Induced X- ray Emission) at the NSLS (National Synchrotron Light Source) in BNL ( Brookhaven National Laboratory) and by means of PIXE at INP (Institute of Nuclear Physics) in Cracow. According to the physician's investiga tions, cadmium plays a role in oxidation process during tumor growth. Also the other elements i.e. selenium plays here a significant role. T he results obtained so far seem to be interesting and may confirm our hypothesis about the cancer process in the kidney, the hypothesis will be a subject of further study. The applied analytical technique enabl es us to analyze with high precision even a small region of samples.