IN-VIVO MEASUREMENT OF TITANIUM RELEASE BY PIXE

Citation
Y. Tsuboi et al., IN-VIVO MEASUREMENT OF TITANIUM RELEASE BY PIXE, Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 109, 1996, pp. 345-349
Citations number
7
Categorie Soggetti
Physics, Nuclear","Nuclear Sciences & Tecnology","Instument & Instrumentation
ISSN journal
0168583X
Volume
109
Year of publication
1996
Pages
345 - 349
Database
ISI
SICI code
0168-583X(1996)109:<345:IMOTRB>2.0.ZU;2-C
Abstract
The concentration of titanium in soft tissues adjacent to titanium imp lants was measured by PIXE, 12 weeks after the placement of pure titan ium implants in rat abdominal wall. Tissue response adjacent to implan ts; fibrous capsule thickness and number of cells, were also histologi cally analyzed. The results showed that the concentration of titanium in the fibrous capsule was less than 10 ppm irrespective to surface ro ughness of implants at the mu m level. PIXE measurement is a useful me thod for the detection and quantification of trace elements when appli ed simultaneously with histomorphometric analysis.