S. Yin et al., STUDY ON THE CHANGES OF METAL ELEMENTAL CONTENTS IN WHOLE-BLOOD AND BONE DURING FRACTURE-HEALING, Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 109, 1996, pp. 358-361
The radii of 72 rabbits were fractured by operation and the contents o
f elements P, S, K, Ca, Fe, Ni, Cu and Zn in whole blood of the rabbit
s during fracture healing were determined by proton induced X-ray emis
sion (PIXE). The contents of Ca and Fe in whole blood were almost kept
constant and the contents of other elements varied significantly duri
ng fracture healing. The contents of elements K, Ca, Mn, Fe, Cu and Zn
in bone far 48 rabbits fractured in radius of limb during healing wer
e also analyzed by PIXE. Various absorbers were tested to improve the
PIXE spectra of bone samples and the spectra with much better quality
were obtained using some kinds of combined absorbers. The changes of t
he contents of elements Sr and Fe in bone were shown as a concave shap
e and convex one respectively, during healing period.