A GENERAL-ROUTE FOR THE SYNTHESIS OF PYRIMIDO[4',5' 4,5]THIENO[2,3-C]PYRIDAZINE DERIVATIVES/

Authors
QUINTELA JM VEIGA MC CONDE S PEINADOR C
Citation
Jm. Quintela et al., A GENERAL-ROUTE FOR THE SYNTHESIS OF PYRIMIDO[4',5' 4,5]THIENO[2,3-C]PYRIDAZINE DERIVATIVES/, Monatshefte fuer Chemie, 127(6-7), 1996, pp. 739-745
Citations number
26
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
127
Issue
6-7
Year of publication
1996
Pages
739 - 745
Database
ISI
SICI code
0026-9247(1996)127:6-7<739:AGFTSO>2.0.ZU;2-V
Abstract
A facile synthesis of 8-substituted pyrimido[4',5':4,5]thieno[2,3-c]py ridazines (6a-i) has been accomplished. The sequence involves the ring closure of a heterocyclic aminonitrile precursor (3) after reaction w ith (dichloromethylene)-dimethylammonium chloride.