Objective-To determine the 11 year outcome of neurotic disorder in gen
eral practice. Design-Cohort study over 11 years. Setting-Two general
practices in Warwickshire England. Subjects-100 patients selected to b
e representative of those identified nationally by general practitione
rs as having neurotic disorders. Main outcome measures-Mortality, morb
idity, and use of health services. Results-At 11 years 87 subjects wer
e traced. The 11 year standardised mortality ratio was 173 (95% confid
ence interval 164 to 200). 47 were cases on the general health questio
nnaire, 32 had a relapsing or chronic psychiatric course, and 49 a rel
apsing or chronic physical course. Treatment for psychiatric illness w
as mainly drugs. The mean number of consultations per year was 10.8 (m
edian 8.7). A persistent psychiatric diagnosis at one year follow up w
as associated with high attendance (>12 visits a year for 11 years) at
follow up after age, sea, and physical illness were adjusted for. Sev
erity of psychiatric illness (general health questionnaire score) at o
utset predicted general health questionnaire score at 11 year follow u
p, course of psychiatric illness, and high consultation rate. Conclusi
on-These data support the view that a neurotic illness can become chro
nic and is associated with raised mortality from all causes and high u
se of services. Such patients need effective intervention, particularl
y those with a more severe illness who do not recover within one year.