Aim of this study was to validate the Italian version of the Brief Pai
n Inventory (BPI), Breve Questionario per la Valutazione del Dolore (B
QVD), which is a multidimensional instrument to assess pain intensity
and pain interference with daily functions. A group of 110 patients wi
th cancer pain were enrolled in the study and were administered the BV
QD and the Therapy Impact Questionnaire (TIQ) which is a valid instrum
ent for quality of life assessment in cancer patients. Cronbach's alph
as were computed for the interference and severity scales in assessing
reliability. Confirmatory factor analysis was utilized to ascertain c
onstruct validity of the BQVD, Measures of interference and of intensi
ty were calculated a priori from the TIQ results and were used in corr
elated correlations. Alpha coefficients for the pain severity and the
pain interference scale were above 0.75, Confirmatory factor analysis
showed that a 2-factor solution for the BQVD structure was interpretab
le and provided adequate fit for the data, The correlation with the TI
Q items showed a stronger association between factor 1 (interference)
and the interference with affect and activity measure from the TIQ, wh
ile factor 2 (severity) was more strongly associated with the TIQ pain
severity measure, In comparison with other non-italian samples our re
sults show a lower reliability estimate, Overall the analysis of these
data shows that the BQVD is a useful and valid tool in assessing pain
and its impact on patients' quality of life which could also help in
developing international and cross-cultural studies in cancer pain.