E. Jonsson et al., LACK OF ASSOCIATION BETWEEN SCHIZOPHRENIA AND THE APOLIPOPROTEIN E-EPSILON-4 ALLELE, European archives of psychiatry and clinical neuroscience, 246(4), 1996, pp. 182-184
The association between the epsilon 4 allele of the apolipoprotein E (
APOE) gene and Alzheimer's disease (AD) has been reported. In order to
examine if the epsilon 4 allele may play a role also in schizophrenia
, another mental disorder, patients (n = 87) and control subjects (n =
57) were genotyped for APOE. No significant difference was found betw
een the groups. The data indicate that the APOE gene is not of major i
mportance for the genesis of schizophrenia.