STRUCTURAL ORGANIZATION OF THE HUMAN CGMP PHOTORECEPTOR PHOSPHODIESTERASE BETA-SUBUNIT GENE

Authors
SUSLOVA VA SUSLOV ON KIM EE LIPKIN VM
Citation
Va. Suslova et al., STRUCTURAL ORGANIZATION OF THE HUMAN CGMP PHOTORECEPTOR PHOSPHODIESTERASE BETA-SUBUNIT GENE, Bioorganiceskaa himia, 22(4), 1996, pp. 256-263
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
22
Issue
4
Year of publication
1996
Pages
256 - 263
Database
ISI
SICI code
0132-3423(1996)22:4<256:SOOTHC>2.0.ZU;2-A
Abstract
Two recombinant bacteriophage lambda clones encoding a 27.8-kb fragmen t of the human phosphodiesterase beta-subunit gene were isolated from a human genomic library. The nucleotide sequences of 19 exons (from th e 4th to 22nd), 18 introns,and the 3'-flanking region were determined. The analysis of the nucleotide sequence of the phosphodiesterase beta -subunit gene revealed four Alu repeats and four minisatellite regions .