S. Asgarali et al., THE TREATMENT OF RECURRENCE FOLLOWING FAST-NEUTRON THERAPY FOR BEAD AND NECK MALIGNANCY, Clinical otolaryngology and allied sciences, 21(3), 1996, pp. 274-277
Twenty-eight patients received fast neutron therapy for head and neck
malignancy. Of these, seven had no recurrence, 13 had a recurrence at
the primary site, five had a recurrence in the neck and three had a re
currence in the neck and at the primary site. Treatment of a primary s
ite recurrence was difficult with seven of the eight patients submitte
d for major surgical resection developing serious complications. Of th
e six patients developing a fistula four required flap repair. The tum
our specific 5-year survival for the whole group of 28 patients was 29
%. The surgical treatment of locoregional recurrence following fast ne
utron therapy is fraught with problems and some type of flap repair is
usually necessary.