Ts. Steiner et Rl. Guerrant, THE PATHOGENESIS OF AND HOST RESPONSE TO CRYPTOSPORIDIUM-PARVUM, Current opinion in infectious diseases, 9(3), 1996, pp. 156-160
Cryptosporidium parvum is emerging as an important and problematic cau
se of diarrhea throughout the world. The lack of effective treatment o
r prophylaxis make the study of this organism a high priority. This re
view outlines the most recent developments in the understanding of cry
ptosporidiosis, especially with regard to pathogenesis, the immune res
ponse to infection, and the contribution of host factors to the sympto
ms of the disease. New paradigms of drinking water treatment and impro
ved understanding of the immunopathogenesis of cryptosporidiosis are k
ey to the control of this important emerging protozoal disease.