AVASCULAR NECROSIS FOLLOWING EXTENSIVE CHEMOTHERAPY AND DEXAMETHASONETREATMENT IN A PATIENT WITH ADVANCED OVARIAN-CANCER - CASE-REPORT ANDREVIEW OF THE LITERATURE
H. Gogas et D. Fennelly, AVASCULAR NECROSIS FOLLOWING EXTENSIVE CHEMOTHERAPY AND DEXAMETHASONETREATMENT IN A PATIENT WITH ADVANCED OVARIAN-CANCER - CASE-REPORT ANDREVIEW OF THE LITERATURE, Gynecologic oncology, 63(3), 1996, pp. 379-381
Avascular necrosis has long been recognized as a complication of gluco
rticoid therapy. With the recent recognition of paclitaxel's activity
in advanced ovarian cancer, increasing attention has been focused on t
he concomitant use of corticosteroid premedication and its associated
morbidities. This report describes avascular necrosis occurring in a p
atient receiving chemotherapy with corticosteroid medication for advan
ced recurrent ovarian cancer. (C) 1996 Academic Press, Inc.