Cf. Cox et al., BIOCOMPATIBILITY OF VARIOUS DENTAL MATERIALS - PULP HEALING WITH A SURFACE SEAL, The International journal of periodontics & restorative dentistry, 16(3), 1996, pp. 241-252
Class V cavities with mechanical exposures were prepared in 178 teeth
of seven monkeys to observe the temporal healing of exposed pulps in d
irect contact with various dental materials, with or without a biologi
c seal of zinc-oxide eugenol cement against microleakage. Thirty pulps
were direct capped as calcium hydroxide controls. The remaining 148 e
xposures were direct capped, 41 with silicate 39 with zinc phosphate,
33 with amalgam, and 35 with an auto-cured composite. Sixty-four were
restored to their cavosurface margin with their respective material an
d 84 were sealed to the cavosurface margin with zinc-oxide eugenol cem
ent. Tissues were obtained by perfusion fixation at intervals of 35, 2
1, 14, 10, 5, and 3 days, and then processed and evaluated. The result
s of this study demonstrated that exposed dental pulps possess an inhe
rent healing capacity allowing cell reorganization and dentin bridge f
ormation when adequately sealed with zinc-oxide eugenol cement to prev
ent bacterial microleakage.