LOCALIZED SCLERODERMA IN BREAST-CANCER PATIENTS TREATED WITH SUPERVOLTAGE EXTERNAL-BEAM RADIATION - RADIATION PORT SCLERODERMA

Background: An association between systemic scleroderma, radiation, an d breast cancer has been recognized. However, localized scleroderma in the radiation port of breast cancer patients has been rarely describe d. Objective: Our purpose was to describe the concurrence of localized scleroderma, supervoltage radiation, and breast carcinoma. Methods: P atients were prospectively evaluated in a tertiary care cancer center, and the Literature was reviewed. Results: We describe six patients wi th breast cancer in whom localized scleroderma developed within their radiation port. Conclusion: Radiation port localized scleroderma can b e a sequela of supervoltage radiation therapy in patients with breast cancer. Recognition is important because localized scleroderma can cli nically mimic recurrent breast carcinoma.