Literature on head and neck oncology continues to support the use of l
asers in surgery of malignant and premalignant lesions of the oral cav
ity. This article explores the indications, techniques, results, and c
omplications of laser use for surgery involving these lesions. Highlig
hted is the carbon dioxide laser, which is well suited for transoral r
esections of premalignant lesions and early carcinomas in the oral cav
ity. In this study the local control, the 5-year survival rates, and t
he postoperative function with the carbon dioxide laser are at least c
omparable with those obtained using other surgical methods. The neodym
ium:ttrium-aluminum-garnet laser, which has specific advantages in the
treatment of large vascular malformations of the oral cavity because
of its unique characteristics, is also discussed.