REDUCTION OF AROMATIC NITROCOMPOUNDS BY SODIUM-BOROHYDRIDE IN METHANOL IN THE PRESENCE OF SODIUM METHOXIDE

Authors
SUWINSKI J WAGNER P HOLT EM
Citation
J. Suwinski et al., REDUCTION OF AROMATIC NITROCOMPOUNDS BY SODIUM-BOROHYDRIDE IN METHANOL IN THE PRESENCE OF SODIUM METHOXIDE, Tetrahedron, 52(28), 1996, pp. 9541-9552
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
52
Issue
28
Year of publication
1996
Pages
9541 - 9552
Database
ISI
SICI code
0040-4020(1996)52:28<9541:ROANBS>2.0.ZU;2-W
Abstract
The paper presents the results of the reduction of 1-nitroimidazoles, 4-nitropyrasoles and 3-nitropyridines by sodium borohydride or sodium borodeuteride in methanol in the presence of sodium methoside. 1-subst ituted 4-nitroimidazoles yield oximes of 4-imidazolidinones, the nitro pyrazoles and nitropyridines yield respective azoxy compounds. The rea ction mechanism proposed in the work makes allowances for catalytic ef fect of the system methanol-methoxide. Copyright (C) 1996 Elsevier Sci ence Ltd