ROLE OF FIBRIN SEALANTS IN SURGICAL-PROCEDURES ON PATIENTS WITH HEMOSTATIC DISORDERS

Fibrin sealants have until now been used to a very limited extent in p atients with a bleeding diathesis, The authors have accumulated experi ence from 8 minor and 40 major surgical procedures, plus 10 circumcisi ons and 118 tooth extractions in 106 patients suffering from hemophili a A, B, or von Willebrand's disease, Most of the patients had the seve re form of the disease, The authors were able to show a reduction of b lood loss and of requirements for replacement therapy with factor conc entrates, The literature on the application of fibrin sealants in this group of patients, which mainly deals with dental procedures, is revi ewed and compared with data from the current study, The composition of the glue is of major significance and is discussed in detail.