This paper reviews research published in recent years concerning the e
ffects of zinc and iron interaction in both animal and humans. The inf
ormation is discussed with particular emphasis on those situations rel
evant to the realities of less-industrialized countries. A clear need
for a shift from the naked concept of ''deficiency'' or ''excess'' to
a global perspective of ''balance'' emerges from the analysis performe
d. The conceptual considerations made here may have application beyond
these two nutrients when approaching solutions for the correction of
nutritional disorders. Copyright (C) 1996 Elsevier Science Inc.