Lermoyez's syndrome is usually regarded as a rare variant of Meniere's
disease with hearing improvement and reduction of tinnitus during ver
tiginous attacks. Electrocochleographic studies of this syndrome are r
estricted to one published case up to now. Methods: In our ENT departm
ent we clinically and electrocochleographically examined three patient
s suffering from Lermoyez's syndrome. These results were compared to t
hose typically found in Meniere patients. Results: Two of the three pa
tients did not show an elevated summating potential or increased ratio
of summating potential and compound action potential (SP/CAP ratio).
There was no hearing improvement following oral glycerol administratio
n, and the SP/CAP ratio did not change during a Lermoyez attack. On th
e other hand, we observed normal cochlear microphonics in ears affecte
d by Lermoyez's syndrome, indicating good hair cell function. In one e
ar, the threshold of cochlear microphonics was even better than the pu
re tone threshold. Conclusions: Our observations suggest that endolymp
hatic hydrops may not be always the underlying pathologic correlate of
Lermoyez's syndrome. Thus Lermoyez's syndrome should not be simply re
garded as a variant of Meniere's disease.