BACKGROUND: Gastric outlet obstruction secondary to chronic duodenal u
lceration is an indication for surgery as conservative management with
balloon dilatation frequently fails. The standard operation is trunca
l vagotomy and a drainage procedure. However, development of minimally
invasive surgery has revolutionized the surgical approach to this cli
nical problem. METHODS: Twelve male patients with pyloric stenosis sec
ondary to duodenal ulceration underwent laparoscopic truncal vagotomy
and gastrojejunostomy. The perioperative and long term outcome of this
group of patients were analyzed. RESULTS: The median operating time w
as 210 (range 180 to 240) minutes. Median postoperative stay was 6 (ra
nge 4 to 41) days. Conversion to laparotomy was necessary in one patie
nt. Delayed gastric emptying occurred in two patients but resolved on
conservative measures. At a median postoperative followup of 6 (range
1 to 12) months all patients had a good symptomatic outcome (Visick gr
ades I or II). CONCLUSIONS: Laparoscopic truncal vagotomy and gastroje
junostomy is a feasible technique. Intermediate followup shows good sy
mptomatic results when used for pyloric stenosis.