TRANSFERABLE CEFOXITIN RESISTANCE IN ENTEROBACTERIA FROM GREEK HOSPITALS AND CHARACTERIZATION OF A PLASMID-MEDIATED GROUP-1 BETA-LACTAMASE (LAT-2)

Authors
GAZOULI M TZOUVELEKIS LS PRINARAKIS E MIRIAGOU V TZELEPI E
Citation
M. Gazouli et al., TRANSFERABLE CEFOXITIN RESISTANCE IN ENTEROBACTERIA FROM GREEK HOSPITALS AND CHARACTERIZATION OF A PLASMID-MEDIATED GROUP-1 BETA-LACTAMASE (LAT-2), Antimicrobial agents and chemotherapy, 40(7), 1996, pp. 1736-1740
Citations number
26
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
40
Issue
7
Year of publication
1996
Pages
1736 - 1740
Database
ISI
SICI code
0066-4804(1996)40:7<1736:TCRIEF>2.0.ZU;2-W
Abstract
Cefoxitin resistance in Klebsiella pneumoniae and Escherichia coli str ains isolated in Greek hospitals was found to be due to the acquisitio n of similar plasmids coding for group 1 beta-lactamases. The plasmids were not self-transferable but were mobilized by conjugative plasmids . These elements have also been spread to Enterobacter aerogenes, The most common enzyme was a Citrobacter freundii-derived cephalosporinase (LAT-2) which differed from LAT-1 by three amino acids.