TEMPORALLY CHANGING PATTERNS OF HIPPOCAMPAL CEREBRAL GLUCOSE-UTILIZATION FOLLOWING SENSORIMOTOR CORTICAL CONTUSION IN RATS

Authors
QUEEN SA FEENEY DM
Citation
Sa. Queen et Dm. Feeney, TEMPORALLY CHANGING PATTERNS OF HIPPOCAMPAL CEREBRAL GLUCOSE-UTILIZATION FOLLOWING SENSORIMOTOR CORTICAL CONTUSION IN RATS, Brain research, 724(2), 1996, pp. 246-250
Citations number
53
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
724
Issue
2
Year of publication
1996
Pages
246 - 250
Database
ISI
SICI code
0006-8993(1996)724:2<246:TCPOHC>2.0.ZU;2-5
Abstract
Unilateral sensorimotor cortical contusion significantly decreased ips ilateral hippocampal cerebral metabolic rates of glucose utilization ( CMR(glu)) compared to sham controls at 2 and 16 days post injury. In c ontrast, hippocampal CMR(glu) was transiently increased at 6 days post injury. Both the increased and decreased CMR(glu) were predominantly localized to the hippocampal CA3 subfield ipsilateral to injury and we re significantly different from sham controls in the dorsal but not ve ntral hippocampal formation.