Sa. Queen et Dm. Feeney, TEMPORALLY CHANGING PATTERNS OF HIPPOCAMPAL CEREBRAL GLUCOSE-UTILIZATION FOLLOWING SENSORIMOTOR CORTICAL CONTUSION IN RATS, Brain research, 724(2), 1996, pp. 246-250
Unilateral sensorimotor cortical contusion significantly decreased ips
ilateral hippocampal cerebral metabolic rates of glucose utilization (
CMR(glu)) compared to sham controls at 2 and 16 days post injury. In c
ontrast, hippocampal CMR(glu) was transiently increased at 6 days post
injury. Both the increased and decreased CMR(glu) were predominantly
localized to the hippocampal CA3 subfield ipsilateral to injury and we
re significantly different from sham controls in the dorsal but not ve
ntral hippocampal formation.