The application of stents for treatment of peripheral arterial occlusi
ve disease has gained widespread clinical use, but their safety and ef
ficacy remain unclear. Stent technology is still evolving, and long-te
rm follow-up data are sorely needed. Stents have had good success in p
roviding a scaffold to maintain the intraluminal structure and patency
of an artery. As such, stents appear to play a role in improving earl
y results after failed or inadequate balloon angioplasty. However, ste
nts do not prevent restenosis due to intimal hyperplasia. Furthermore,
stents may be thrombogenic and prone to extrinsic compression in the
peripheral position. Thus patency results are clearly worse in the fem
oral artery (47% at 3 years) than in the iliac artery (82-84% at 6-24
months). Furthermore, there is no evidence so far that stents improve
long-term patency over standard balloon angioplasty without stents; an
d complication rates of stent procedures are generally 10%. Currently
in the United States stents are approved for use in the iliac artery p
osition. However, routine use of stents cannot be recommended until st
udies demonstrate that the results with stents are better than those w
ith balloon angioplasty alone.