SYNTHESIS OF ALPHA-(TRIFLUOROMETHYL) PHENYLACETONITRILE - ANOMALOUS REACTIONS OF TOSYLOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETONITRILE WITH SODIUM-BOROHYDRIDE

Authors
NEMETH G POSZAVACZ L BOZSING D SIMIG G
Citation
G. Nemeth et al., SYNTHESIS OF ALPHA-(TRIFLUOROMETHYL) PHENYLACETONITRILE - ANOMALOUS REACTIONS OF TOSYLOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETONITRILE WITH SODIUM-BOROHYDRIDE, Journal of fluorine chemistry, 78(1), 1996, pp. 87-89
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
78
Issue
1
Year of publication
1996
Pages
87 - 89
Database
ISI
SICI code
0022-1139(1996)78:1<87:SOAP-A>2.0.ZU;2-U
Abstract
The hitherto unknown alpha-(trifluoromethyl)phenylacetonitrile has bee n synthesized by reduction of the cyanohydrin of alpha,alpha,alpha-tri fluoroacetophenone. Sodium borohydride reduction of the corresponding cyanohydrin tosylate resulted in reductive decyanation in dimethyl sul phoxide and in reduction of the nitrile group in t-butanol.