PARASITE GLYCOCONJUGATES .5. BLOCKWISE APPROACH TO OLIGO(GLYCOSYL PHOSPHATES) - CHEMICAL SYNTHESIS OF A TERMINAL TRIS(GLYCOBIOSYL PHOSPHATE) FRAGMENT OF LEISHMANIA-DONOVANI ANTIGENIC LIPOPHOSPHOGLYCAN
Av. Nikolaev et al., PARASITE GLYCOCONJUGATES .5. BLOCKWISE APPROACH TO OLIGO(GLYCOSYL PHOSPHATES) - CHEMICAL SYNTHESIS OF A TERMINAL TRIS(GLYCOBIOSYL PHOSPHATE) FRAGMENT OF LEISHMANIA-DONOVANI ANTIGENIC LIPOPHOSPHOGLYCAN, Journal of the Chemical Society. Perkin transactions. I, (13), 1996, pp. 1559-1566
The model tetramannosyl triphosphate 7 and the hexaglycosyl triphospha
te 8, which is a terminal fragment of the phosphoglycan portion of Lei
shmania donovani lipophosphoglycan, have been synthesized. Elongation
of the chain was performed using the glycosyl hydrogenphosphonate meth
od to couple together two phosphodiester blocks.