M. Ghesani et al., IMPORTANCE OF DRESSING REMOVAL BEFORE RADIOLABELED WBC IMAGING FOR MUSCULOSKELETAL INFECTION, Clinical nuclear medicine, 21(7), 1996, pp. 537-540
Leukocyte imaging performed with In-ill or Tc-99m is gaining widesprea
d acceptance as a method for detection of osteomyelitis associated wit
h soft tissue injury or infection, The authors present three cases in
which initial imaging was suggestive of a focal infectious process in
bone and soft tissue, However, repeat imaging after the removal of wou
nd dressings, which revealed serosanguineous discharge in all cases, r
esulted in a scan appearance that was much less remarkable for focal r
adiotracer accumulation in the bone, The authors conclude that accumul
ation of labeled WBCs in wound discharge can result in scans that are
false-positive for osteomyelitis. Therefore, the authors recommend tha
t wounds should be cleaned and dressings changed before imaging in ord
er to avoid scans that are false-positive for osteomyelitis.