H. Dautzenberg et al., IMMOBILIZATION OF BIOLOGICAL MATTER BY POLYELECTROLYTE COMPLEX-FORMATION, Berichte der Bunsengesellschaft fur Physikalische Chemie, 100(6), 1996, pp. 1045-1053
Citations number
28
Categorie Soggetti
Chemistry Physical
Journal title
Berichte der Bunsengesellschaft fur Physikalische Chemie
The immobilisation of biological matter plays an important part in cre
ating biologically active systems for applications preferably in biote
chnological processes or in medical treatments. The immobilisation by
polyelectrolyte complex formation, allowing the encapsulation of sensi
tive biological objects or materials without causing any damage to the
m, has become a powerful alternative method. In more detail experiment
al results on capsule formation with sodium cellulose sulphate and pol
y(diallyldimethylammonium chloride) as reaction compounds are reported
. Capsule formation and capsule properties (morphological features, cu
t-off, rate of NaCS conversion, size and mechanical stability) are loo
ked at under polymerchemical and physicochemical aspects. The importan
ce of osmotic effects is revealed. It is shown that the capsule proper
ties depend not only on the chemical structure of the polyelectrolytes
or the conditions of capsule preparation, but also remarkably on the
polymerchemical characteristics of the reaction components, particular
ly on their molecular mass and/or molecular mass distribution.